Myths vs facts: Skincare DNA and allergy

Claims that a skincare DNA test can predict or prevent allergies are poorly supported by evidence. While some genetic variants (e.g., FLG for filaggrin) are linked to skin sensitivity and allergies, effect sizes are small and predictive value for individual allergies is insufficient. Most commercial tests rely on small studies or GWAS with population-specific limitations. Allergies arise from a complex interplay of genetics, environment, microbiome, and immune system – a simple DNA test cannot capture this. Moreover, no randomized controlled trials show that skincare based on such tests actually prevents allergies. Evidence is best classified as 'marketing' or 'unclear'. Consumers should view these tests as curiosity, not medical diagnosis. For real allergy symptoms, consult an allergist or dermatologist.