Evidence check: CRP Entzündung in the context of Darmgesundheit

CRP (C-reactive protein) is a non-specific inflammatory marker produced by the liver. Elevated CRP can indicate systemic inflammation from infections, autoimmune conditions, or lifestyle factors. In the context of gut health, there is evidence that impaired gut barrier function ('leaky gut') and microbiome dysbiosis may contribute to low-grade systemic inflammation, potentially reflected in moderately elevated CRP. However, the evidence is largely observational and not strong enough to recommend CRP as a specific marker for gut health. MyBody-X tests do not directly measure CRP; they analyze microbiome or DNA. Genetic variants such as rs174546 in the FADS1 gene can influence omega-3/6 desaturation and thus indirectly affect inflammatory regulation, but the effect on CRP is small and often clinically insignificant. For reliable assessment of gut health, more specific markers (e.g., fecal calprotectin) or functional tests are appropriate. CRP remains a general screening parameter and should not be used in isolation to diagnose gut issues.