Can HbA1c help with Langlebigkeit?

HbA1c (glycated hemoglobin) is a well-established biomarker reflecting average blood glucose over the past 2–3 months. Strong epidemiological evidence links elevated HbA1c to increased risk of age-related diseases such as type 2 diabetes, cardiovascular disease, and cognitive decline – all factors that impact lifespan and healthspan. However, HbA1c is not a direct 'longevity marker'. An optimal range (e.g., 5.0–5.6% in healthy individuals) may indicate good metabolic health, but very low levels (<4.5%) are associated with higher mortality (J-shaped curve). Its predictive value is limited because HbA1c can be confounded by anemia, kidney disease, or hemoglobin variants. For a comprehensive longevity assessment, HbA1c should be interpreted alongside other markers (fasting insulin, lipids, inflammatory markers). The provided context lacks specific sources on HbA1c and longevity, so this assessment is based on widely accepted evidence. Caveat: A single HbA1c value alone is not a sufficient predictor of individual life expectancy.