When is Stuhlprobe Genetik actually useful?

Stool sample genetics (microbiome analysis) is an emerging field in personalized medicine, but its clinical utility remains limited. It can provide insights into gut flora composition, which may be relevant in suspected dysbiosis (e.g., after antibiotics, in irritable bowel syndrome). However, standardized reference ranges and robust clinical trials proving clear diagnostic or therapeutic benefit are lacking. Many commercial tests combine validated IgE measurements (for allergies) with unvalidated IgG tests (for intolerances), leading to misinterpretation and unnecessary dietary restrictions. Stool genetics (e.g., bacterial DNA analysis) is not a routine test and should only be performed in specialized centers with expert counseling. Without medical supervision, there is a risk of overdiagnosis and wasted expense. Evidence: mixed/unclear.