The question of which supplements make sense cannot be answered universally. MyFoodBook aims to recommend supplements based on individual data (DNA, blood markers, microbiome). However, the evidence for many supplements is weak: vitamin D for confirmed deficiency is well-supported, as is omega-3 (EPA/DHA) for low fish intake – a genetic test for FADS1 variants can provide hints, but the effect is small. For 'anti-aging' supplements like collagen or glycation inhibitors, long-term clinical data are lacking; DNA tests for collagen genes (MMP1, COL1A1) show only small effects. Probiotics are usually unnecessary for healthy individuals but may help after antibiotics. Beware of exaggerated claims: many tests are marketing, not medicine. Supplements are sensible only when a verified deficiency or specific risk factor exists – and always in consultation with a physician. The overall evidence level is 'mixed'.
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