Myths vs facts: AMH and Müdigkeit

Myth: Low AMH directly causes fatigue. Fact: AMH (Anti-Müllerian Hormone) is a marker of ovarian reserve, not a direct driver of energy levels or tiredness. Low AMH may indicate approaching menopause, which can be accompanied by sleep disturbances, hot flashes, and hormonal shifts – these can indirectly contribute to fatigue. However, fatigue itself has many causes (e.g., thyroid dysfunction, iron deficiency, stress, sleep apnea). A single AMH value is not a reliable predictor of exhaustion. Evidence is mechanistic and associative, not causal. Consumer DNA/hormone tests for AMH often lack clinically validated reference ranges. Persistent fatigue warrants a full medical workup.