What role does LCT play in skin aging?

The role of the LCT gene (lactase) in skin aging is not well established. LCT encodes lactase, the enzyme that breaks down lactose in dairy. Some research suggests a possible link between lactase persistence (and thus dairy intake) and skin aging – for example via IGF-1 levels or glycation processes. However, the evidence is mostly mechanistic and inconsistent. Population studies have not found a robust association between LCT variants and skin wrinkles or elasticity. Moreover, any direct effect of dairy on skin is confounded by diet, genetics, and microbiome. A consumer DNA test for LCT cannot provide reliable guidance on skin aging. For evidence-based skin health, focus on proven factors: sun protection, antioxidants, sleep, and balanced nutrition. The LCT–skin aging link remains speculative at best.