Can Insulin help with weight loss?

Insulin is an anabolic hormone that promotes glucose uptake and fat storage. Exogenous insulin (e.g., in diabetes) typically causes weight gain, not loss. In non-diabetic individuals, using insulin for weight loss is dangerous and can lead to hypoglycemia and metabolic disturbances. The notion contradicts established physiology. Improving insulin sensitivity through diet, exercise, and weight loss is effective, but taking insulin does not help shed pounds. Evidence is strong: insulin promotes lipogenesis and inhibits lipolysis. Therefore, insulin is not a weight-loss aid.