Women’s Wellness Check | Frauen-Gesundheits-Test: can a microbiome test help?

A microbiome test can provide supplementary information in a Women’s Wellness Check, especially regarding vaginal or gut flora. However, the evidence for actionable recommendations from such tests is still limited. Research shows associations between the microbiome and gynecological conditions like bacterial vaginosis or urinary tract infections, but routine use for general wellness screening is not recommended by current guidelines. The provided context lacks specific studies or genes that directly support a benefit. Moreover, many commercial microbiome tests are not standardized, and interpretation is challenging because the microbiome is highly influenced by diet, lifestyle, medications, and hormonal status. A test may serve as a screening tool but should not be interpreted without medical guidance. In asymptomatic women, the benefit is particularly unclear. The evidence level is therefore rated as 'unclear', as this is an evolving field with mechanistic and early clinical data but no robust randomized trials for wellness screening.