TSH (thyroid-stimulating hormone) is a key marker of thyroid function. A well-functioning thyroid is crucial for fertility, as thyroid hormones influence menstrual cycles, ovulation, and sperm quality. TSH levels outside the normal range (e.g., >2.5 mIU/L when trying to conceive) may indicate hypothyroidism or hyperthyroidism, both of which can impair fertility. Importantly, TSH itself is not a treatment; it is a diagnostic hormone. In cases of hypothyroidism, levothyroxine (thyroid hormone) is prescribed to normalize TSH and improve fertility outcomes. The evidence linking thyroid function to fertility is strong (human-strong). However, TSH is just one piece of the puzzle; other factors like prolactin, estradiol, and semen analysis are also important. Measuring TSH can help identify a treatable cause of infertility, but it does not replace a comprehensive fertility workup. Caveat: For those planning pregnancy, the optimal TSH target should be discussed with an endocrinologist, as individual needs may vary.
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