Myth: A genetic test for celiac disease (e.g., HLA-DQ2/DQ8) can confirm or rule out the condition. Fact: Absence of HLA-DQ2/DQ8 virtually excludes celiac, but presence is not diagnostic – only about 30% of carriers develop celiac. Diagnosis requires duodenal biopsy and serology (tTG-IgA). Myth: Celiac tests (blood or stool) directly explain sleep problems. Fact: Untreated celiac can impair sleep via malabsorption, nutrient deficiencies (iron, vitamin D, B12), or associated conditions (restless legs syndrome, sleep apnea). However, a positive test does not automatically account for sleep disturbances – other causes are common. Consumer DNA tests for celiac risk provide only a probability, not a diagnosis. If you have sleep issues and suspect celiac, consult a physician for proper workup. Evidence: human-moderate (association celiac-sleep, but test alone insufficient).
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