How are Magnesium and fertility related?

Magnesium is an essential mineral involved in over 300 enzymatic reactions, including hormone regulation, DNA synthesis, and cell division – all relevant to fertility. Studies suggest a link between low magnesium levels and female subfertility, potentially through impaired ovulation or oocyte quality. In men, magnesium is associated with improved sperm motility and concentration, as it supports antioxidant defenses and reduces oxidative stress. However, the evidence is moderate: most data come from observational or small intervention studies, not large randomized controlled trials. A direct causal effect is not proven, and individual response depends on baseline status, diet, and genetic factors. Direct-to-consumer tests linking single SNPs (e.g., in TRPM6 or other magnesium transporters) to fertility are largely speculative and not clinically validated. A balanced diet rich in magnesium (whole grains, nuts, leafy greens) is advisable, but supplementation without medical guidance is not recommended. Safety note: excessive magnesium intake can cause diarrhea and electrolyte imbalances.