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What role does tTG IgA play in Allergie?

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What role does tTG IgA play in Allergie?

tTG IgA (tissue transglutaminase IgA) is not a marker for allergies; it is the primary serological test for celiac disease, an autoimmune enteropathy triggered by gluten. In suspected celiac disease, tTG IgA is measured in blood; a positive result requires duodenal biopsy for confirmation. Allergies (e.g., wheat allergy) are IgE-mediated and diagnosed via specific IgE or skin prick tests. Confusing celiac disease with an allergy is common but medically incorrect. tTG IgA plays no role in classic allergies. Note: In IgA deficiency, tTG IgA may be falsely negative, requiring IgG-based tests. MyBody-X does not offer tTG IgA testing; this is clinical laboratory diagnostics.

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