How are Selen and Fruchtbarkeit related?

Selenium is an essential trace element that plays a significant role in both male and female fertility. It is a key component of selenoproteins such as glutathione peroxidases, which protect cells from oxidative stress – a critical factor for egg and sperm quality. Studies indicate that selenium deficiency is associated with reduced sperm motility, increased sperm DNA fragmentation, and a higher risk of miscarriage. In women, selenium supports thyroid function, which in turn influences menstrual regularity and implantation. However, the evidence is not conclusive: some randomized controlled trials show positive effects of selenium supplementation on pregnancy rates, while others find no significant benefit. Moreover, excessive intake (e.g., >200 µg/day) can be toxic and may impair fertility. Most data come from observational studies and small trials; large RCTs are lacking. For healthy individuals with adequate selenium intake (e.g., from Brazil nuts, fish, eggs), additional supplementation is unlikely to provide benefit. A blood test to assess selenium status may be advisable before starting supplements. Overall, the link is biologically plausible, but the clinical evidence is moderate and not generalizable to all populations.