What should I know about MTHFR Genetik?

The MTHFR C677T variant (rs1801133) is a common genetic marker that slightly reduces the activity of the methylenetetrahydrofolate reductase enzyme. This can lead to elevated homocysteine levels, but the effect on disease risk is small – most carriers are healthy. Routine supplementation with methylfolate is not recommended without prior blood testing. Lifestyle factors such as diet, exercise, and stress management have a much larger impact than this single SNP. Consumer tests tend to overstate its importance. Consult a physician before changing any supplement regimen.