Can Folsäure help with allergy?

Whether folic acid (vitamin B9) can help with allergies is not clearly established by current evidence. Some observational studies suggest that adequate folate status during pregnancy may reduce the risk of allergic diseases in offspring, possibly through epigenetic modulation. In adults, folate may influence immune regulation, e.g., by lowering histamine and inflammatory markers. However, randomized controlled trials demonstrating a therapeutic benefit for existing allergies are lacking. The evidence is therefore best described as 'mechanistic' or 'unclear'. Importantly, folic acid is not a substitute for standard allergy treatments (antihistamines, immunotherapy). High-dose folic acid can also mask vitamin B12 deficiency, a risk especially for older adults and vegans. Anyone considering supplementation should have their blood levels tested first. In summary: folic acid is not a proven allergy remedy, but a balanced diet rich in natural folate (leafy greens, legumes) is generally recommended.