Evidence check: Folsäure in the context of longevity

The provided context contains no information on folic acid in relation to longevity. Folic acid (vitamin B9) is essential for cell division and DNA synthesis, but evidence for life extension through supplementation is weak. Some observational studies suggest potential cardiovascular benefits, while randomized controlled trials show no clear advantage for all-cause mortality. Moreover, high folic acid intake may pose risks in individuals with vitamin B12 deficiency. Consumer DNA tests for MTHFR variants are often marketed with exaggerated health claims without clinical validation for longevity. Without direct evidence from the context, the relevance for anti-aging remains unclear. A balanced diet with natural folate sources (e.g., leafy greens) is safer than high-dose supplements.