What should I know about welche unvertraglichkeiten gibt es?

When asking about intolerances, it's important to distinguish between well-established genetic links and overhyped marketing claims. Lactose intolerance (MCM6 variant rs4988235) and celiac disease (HLA-DQ2/DQ8) have strong genetic evidence. Histamine intolerance (DAO gene) and fructose malabsorption have moderate support. However, many direct-to-consumer DNA tests claim to predict gluten sensitivity, lectin intolerance, or reactions to various foods based on single SNPs with weak or conflicting evidence. A DNA test alone cannot diagnose an intolerance; clinical tests like hydrogen breath tests, elimination diets, or blood antibody tests are more reliable. Additionally, the gut microbiome significantly influences food tolerance, which genetics alone cannot capture. Be cautious: eliminating entire food groups without medical guidance can lead to nutrient deficiencies. For a comprehensive approach, combine genetic insights with clinical evaluation and professional dietary advice.