Can Progesteron help with Schlaf?

Progesterone can support sleep, especially in perimenopausal and menopausal women, due to its GABAergic activity that promotes calmness and may improve sleep quality. Evidence is moderate: some RCTs show reduced sleep latency and better sleep efficiency, while others show no benefit. In men or premenopausal women without deficiency, the evidence is weak and use without medical supervision is not advised. Potential side effects (dizziness, mood changes) and interactions with other hormones must be considered. Genetic testing for progesterone receptor variants (e.g., PGR) has no validated role in sleep management. Overall, progesterone is not a first-line sleep aid; it may be helpful only in specific hormonal contexts under medical guidance.