VKORC1 variants primarily affect vitamin K metabolism and sensitivity to anticoagulants like warfarin. A direct link to fertility is not scientifically established. While vitamin K is involved in bone health and coagulation, no robust studies connect VKORC1 polymorphisms to male or female fertility. Some speculate about indirect effects via vitamin K status or placental function, but this remains speculative. Consumer DNA tests like MyBody-X can report your genotype, but interpreting it for fertility is not evidence-based. If you are concerned about fertility, focus on established factors: age, hormone levels, lifestyle, and medical evaluation. Be cautious of marketing claims: VKORC1 is not a fertility gene.
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