Can tTG IgA help with Haut?

tTG IgA (tissue transglutaminase antibody) is a well-established biomarker for celiac disease, an autoimmune condition triggered by gluten. In some patients, celiac disease presents with or exclusively as skin symptoms, most notably dermatitis herpetiformis (Duhring's disease). A positive tTG IgA test can therefore support the suspicion of underlying celiac disease when a compatible skin rash is present. However, it is not a general skin test – most skin conditions have other causes. The evidence for the link between tTG IgA and skin issues is limited to the celiac/dermatitis herpetiformis association, which is well-documented (human-strong). Caveat: a negative tTG IgA does not rule out celiac disease definitively (especially in IgA deficiency or early stage). For unexplained skin problems, a dermatologist should be consulted.