Evidence check: Testosteron in the context of Wechseljahre

Testosterone plays a physiological role in women, influencing libido, bone density, and muscle mass. During menopause, testosterone levels gradually decline, but routine testing is not recommended due to high variability and lack of established reference ranges for this life stage. Evidence for testosterone therapy in menopause is limited: short-term trials show moderate benefits for sexual desire, but long-term safety data (cardiovascular risks, hormone-sensitive cancers) are insufficient. In many countries, including Germany, testosterone is only approved for women under strict medical supervision. A standalone testosterone test without clinical context is of little value and may lead to misinterpretation. Be cautious of marketing claims promoting testosterone as an 'anti-aging miracle.' The evidence base is moderate, relying mostly on observational studies and small RCTs.