What should I know about Cortisol Männer?

Cortisol is a vital hormone that regulates metabolism, immune function, and the stress response. In men, chronically elevated levels—due to persistent stress, poor sleep, or overtraining—can lead to muscle wasting, increased visceral fat, reduced testosterone, and lower libido. The interplay between cortisol and testosterone is complex; an imbalance can negatively affect male health. Currently, no single DNA test reliably predicts cortisol dysregulation; most direct-to-consumer tests rely on weak GWAS associations with small effect sizes. Clinical evaluation (e.g., ACTH stimulation test, dexamethasone suppression) remains the gold standard. Lifestyle interventions—adequate sleep, stress reduction, regular exercise, and a balanced diet—are the most effective ways to maintain healthy cortisol levels. Evidence: human-moderate for general physiology, but for genetic testing: practice/marketing.