Can FUT2 help with Sport?

The FUT2 variant rs601338 determines secretor status and influences vitamin B12 absorption and gut microbiome composition. An indirect link to sports performance is conceivable, as B12 is crucial for energy metabolism and red blood cell formation. However, there are no direct, robust studies connecting FUT2 variants to athletic performance or recovery. The evidence is therefore mechanistic: plausible biological pathways exist, but human performance data are lacking. A FUT2 test may serve as a supplementary hint regarding B12 status or gut health, but not as a sports gene. For athletes, established factors like training, nutrition, and recovery are far more relevant.