Can Leaky Gut Test help with sleep?

A 'Leaky Gut' test measures markers such as zonulin in stool or blood to assess intestinal permeability. The hypothesis that increased gut permeability leads to systemic inflammation, which in turn could impair sleep, is biologically plausible but not well-supported by clinical evidence. No validated reference ranges exist linking these markers to sleep outcomes. The test may indicate a compromised gut barrier, but whether targeted interventions (e.g., probiotics, dietary changes) improve sleep remains unproven. Without accompanying symptoms like bloating or food intolerances, the relevance for sleep issues is uncertain. Evidence: unclear. Source: No direct evidence in provided context; general medical assessment.