Questions people ask about Testosteron Genetik

Testosterone genetics is polygenic, with many SNPs each contributing a tiny effect. Consumer DNA tests often claim to predict testosterone levels using variants in genes like SHBG, CYP19A1, or AR, but the evidence is weak. GWAS show that common variants explain only a small fraction of testosterone variance (e.g., ~2–5 %). These tests are not clinically validated for diagnosis or treatment decisions. Lifestyle factors (sleep, exercise, body fat, stress) and medical conditions (hypogonadism, obesity) have far larger impacts. A blood test measuring total and free testosterone, along with LH and FSH, remains the gold standard. Most direct-to-consumer testosterone genetic reports are marketing-driven and lack actionable insights. Safety note: Do not start hormone therapy based solely on a genetic test; consult an endocrinologist if you have symptoms of low testosterone.