Risks and limits of Kefir Check

The rs5082 variant in the APOA2 gene has been associated in GWAS studies with a slightly higher BMI in response to higher saturated fat intake. However, the effect is small and the evidence is observational, not causal. Reducing saturated fat may be beneficial, but it is not a guarantee against weight gain. Overall diet and lifestyle have a much larger impact. Do not overinterpret this single variant. It does not replace individualized dietary advice.