Evidence check: Cardio Risk Check | Herz-Kreislauf Risiko-Test in the context of fertility

The 'Cardio Risk Check' (cardiovascular risk test) offered by MyBody-X is a DNA or biomarker test. In the context of fertility, there is no direct scientific evidence that this test alone can predict or improve fertility outcomes. While cardiovascular risk factors such as hypertension, obesity, insulin resistance, and dyslipidemia are associated with fertility issues – especially in PCOS or metabolic syndrome – most consumer DNA tests rely on SNPs with very small effect sizes (e.g., rs662799 for triglycerides, beta -0.14). The clinical relevance for individual fertility remains unclear. A positive result for increased cardiovascular risk does not replace a thorough medical workup (blood pressure, lipids, fasting glucose, hormone panel). The evidence for this specific test in a fertility context is weak to mixed. Recommendation: Before fertility treatment, a comprehensive medical evaluation is essential, not just a consumer test.