A celiac test (e.g., tTG-IgA antibodies or genetic test for HLA-DQ2/DQ8) can be useful for sleep issues if accompanied by symptoms like chronic fatigue, unexplained digestive problems, iron deficiency, or skin rash. Untreated celiac disease often disrupts sleep due to systemic inflammation and nutrient deficiencies (e.g., iron, vitamin D). However, screening for celiac based solely on sleep problems without other clues is not medically indicated. Evidence comes from clinical studies and guidelines (e.g., ESPGHAN, ACG) linking celiac disease to poor sleep quality, but only in confirmed cases. Caution: direct-to-consumer tests measuring IgG-based 'gluten sensitivity' are not validated and often lead to false conclusions. A positive celiac test should always be confirmed by a specialist before starting a gluten-free diet. Without clinical signs, the benefit for sleep alone is low.
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