The Omega-3 Index measures EPA+DHA in red blood cells and is a validated biomarker for cardiovascular health. For athletes, an index of 8–12% is often recommended because omega-3s reduce inflammation, support recovery, and may improve muscle function. However, evidence for direct performance enhancement is mixed: some studies show benefits in endurance and reduced muscle soreness, but large athlete-specific RCTs are lacking. Genetic variants (e.g., in FADS1/2) affect the conversion of plant-based ALA to EPA/DHA, meaning some individuals may need more direct sources (fish oil, algae). Caution: high doses (>3 g/day) can increase bleeding risk, especially with anticoagulants. Testing your Omega-3 Index before supplementing is a good practice. Evidence: human-moderate for sport, human-strong for heart health.
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