The question of whether testosterone is useful for menopause is nuanced. Testosterone is sometimes used off-label in menopausal women, primarily for low libido, but also for fatigue and bone health. However, the evidence is limited and mixed. Small studies suggest it may improve sexual desire, but long-term safety and efficacy for other symptoms are not well-established. There are no standardized reference ranges for testosterone in women, and estrogen-based hormone therapy remains the first-line treatment for typical menopausal symptoms. Testosterone therapy should only be considered after thorough medical evaluation and monitoring, as side effects like acne, hirsutism, and voice changes can occur. Direct-to-consumer tests claiming to diagnose testosterone deficiency are often unvalidated and may lead to unnecessary treatments. Overall, the evidence is moderate but not strong enough to recommend routine use.
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