warum nehme ich zu obwohl ich wenig esse — can a DNA test help?

The question of why you gain weight despite eating little is complex. A DNA test can offer clues but not a definitive answer. Genetic variants like FTO (rs9939609) have only a small effect on body weight (a few kg on average) and are strongly modified by lifestyle. Rare mutations in the MC4R gene can cause severe early-onset obesity – but this requires medical evaluation and is not a typical DTC result. Most commercial tests overstate the role of such genes. Other factors – thyroid function, medications, sleep quality, stress, hormones, and possible underestimation of actual calorie intake – play a much larger role. A DNA test can be interesting as part of a comprehensive analysis, but it does not replace a medical workup. The evidence for direct actionable recommendations from genetics is weak. A more useful approach combines biomarker measurements (e.g., fasting insulin, HbA1c) with a food diary.