Can Folsäure help with Allergie?

The question of whether folic acid can help with allergies lacks strong scientific evidence. Folic acid (vitamin B9) is involved in methylation pathways and thus indirectly in immune regulation. Some observational studies suggest a link between low folate levels and increased allergy risk, particularly for asthma and atopic dermatitis. However, these are associations, not causation. Randomized controlled trials demonstrating a therapeutic effect of folic acid supplementation on existing allergies are largely absent. Moreover, high folic acid intake can mask vitamin B12 deficiency, a concern especially for older adults and vegans. From a nutritional perspective, ensuring adequate intake through diet (leafy greens, legumes) is reasonable, but targeted supplementation for allergy treatment is not currently recommended. If a deficiency is suspected, blood levels of folate and homocysteine should be measured first. Evidence: mechanistic, no strong clinical data.