How are Progesteron and Haut related?

Progesterone and skin are linked through hormone receptors in the dermis and epidermis. Progesterone influences sebum production, collagen synthesis, and skin hydration. During the menstrual cycle and pregnancy, elevated progesterone can contribute to acne, melasma, or water retention. In anti-aging medicine, topical progesterone is sometimes used to improve skin elasticity, but the evidence is moderate: small clinical studies and mechanistic work exist, but no large randomized controlled trials. Effects vary individually and depend on other hormones like estrogen. Hormone replacement therapy with progesterone should only be under medical supervision due to potential systemic risks (e.g., thrombosis). In summary: progesterone has demonstrable effects on skin, but clinical application is not evidence-based for all skin concerns. MyBody-X tests for hormone-related genes (e.g., CYP17A1) provide only tendencies, not diagnoses.