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Evidence check: HLA-DQ2 in the context of longevity

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Evidence check: HLA-DQ2 in the context of longevity

HLA-DQ2 is a well-established genetic risk factor for celiac disease, but direct evidence linking it to longevity is lacking. The association with celiac disease is human-strong (clinical), but its effect on lifespan is indirect and context-dependent (e.g., via untreated celiac). Without a diagnosis, the impact on longevity is unclear. Caveat: Do not change diet based solely on this genetic finding.

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