What role does VKORC1 play in Sport?

VKORC1 is a key gene in vitamin K metabolism, affecting blood clotting and bone metabolism. In a sports context, it could theoretically influence bone health (e.g., fracture healing) or recovery from injury. However, there is no strong evidence from sports studies directly linking VKORC1 variants to performance or training outcomes. Most knowledge comes from GWAS on warfarin sensitivity and bone density. A DNA test for VKORC1 variants (e.g., rs9923231) does not provide actionable insights for athletes. The effect sizes are small and not clinically relevant. MyBody-X may include such variants in a comprehensive test, but interpretation remains speculative. Focus should remain on established factors like nutrition (vitamin K, calcium) and training.