What role does hsCRP play in Langlebigkeit?

hsCRP (high-sensitivity C-reactive protein) is a well-established marker of systemic inflammation. In longevity research, chronic low-grade inflammation ('inflammaging') is considered a risk factor for age-related diseases such as cardiovascular disease, diabetes, and cognitive decline. Elevated hsCRP levels are associated with higher all-cause mortality in observational studies. However, hsCRP is not a direct causal marker—it reflects inflammatory processes influenced by lifestyle, diet, exercise, and stress. The evidence is largely epidemiological; randomized trials showing that lowering hsCRP alone extends lifespan are lacking. A normal hsCRP level (<1 mg/L) is considered favorable, but transient elevations due to infections or injuries are common. For personal health optimization, hsCRP is a useful screening tool but not a standalone predictor of longevity. Caveat: home finger-prick tests may have higher variability; abnormal results should be confirmed by a physician.