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Evidence check: Cardio Risk Check | Herz-Kreislauf Risiko-Test in the context of weight loss

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Evidence check: Cardio Risk Check | Herz-Kreislauf Risiko-Test in the context of weight loss

The 'Cardio Risk Check' typically combines genetic markers (e.g., APOE ε4, FOXO3, VDR) with biomarkers like hsCRP and blood lipids. Evidence is mixed: individual components like hsCRP >3 mg/L show strong association with cardiovascular risk (human-strong), while genetic markers like APOE ε4 have moderate effects (human-moderate). In the context of weight loss, these values can improve through lifestyle changes – the test only provides a snapshot. Predictive power for individual events is limited because risk is multifactorial. Caveat: The test does not replace medical diagnosis. Marketing often overstates its utility. Evidence: mixed.

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