When combining a celiac test and blood sugar measurement, several considerations are important. The celiac test (typically IgA antibodies to tissue transglutaminase) requires ongoing gluten consumption; a gluten-free diet can cause false negatives. Blood sugar levels are not directly affected by the test, but there is a well-known association between celiac disease and type 1 diabetes: individuals with type 1 diabetes have an increased risk of celiac disease and vice versa. Additionally, a gluten-free diet can alter carbohydrate metabolism, impacting blood sugar control. Therefore, if blood sugar is abnormal, celiac screening should be considered, and celiac patients should monitor blood sugar regularly. The evidence for these links is moderate, based on clinical studies and guidelines. Caveat: a negative celiac test does not rule out non-celiac gluten sensitivity, and blood sugar fluctuations have many causes.
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