CRP (C-reactive protein) is a non-specific inflammatory marker that rises during infections, tissue damage, and chronic low-grade inflammation. A common myth is that CRP is only relevant for acute infections – in fact, many studies show that chronic sleep deprivation (under 6 hours per night) is associated with elevated CRP levels. The evidence is human-moderate: meta-analyses confirm a significant but modest effect. Another myth: a single CRP test directly reflects sleep quality. The fact is that CRP is influenced by many factors (diet, stress, smoking, BMI). An elevated level may indicate poor sleep, but it is not a specific sleep biomarker. Consumer tests like those from MyBody-X measure CRP in blood or saliva, but interpretation remains limited – they do not replace medical evaluation. To improve sleep, focus on consistent sleep schedules, reducing screen time before bed, and stress management. A CRP test can serve as an additional clue, but not as a standalone diagnosis. Caveat: causal evidence is still inconclusive; some individuals have normal CRP despite sleep deprivation.
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