What role does Leaky Gut Test play in Allergie?

The Leaky Gut Test (often measuring zonulin in stool) is marketed as an indicator of increased intestinal permeability. The hypothesis is that a 'leaky gut' may allow allergens to enter the bloodstream and trigger immune responses. However, the scientific evidence for this causal link in humans is weak. Zonulin levels fluctuate even in healthy individuals, and no standardized cutoffs exist. Therefore, the test cannot diagnose or predict allergies. At best, it provides a mechanistic clue discussed in research. For allergy assessment, established methods like IgE testing or provocation tests are required. Caution: a positive result often leads to unnecessary diets or supplements that lack evidence. If you suspect an allergy, consult an allergist.