What role does TSH Schilddrüse play in longevity?

The thyroid gland and its regulating hormone TSH (thyroid-stimulating hormone) play a complex role in metabolism and potentially in longevity. Optimal TSH levels are important for maintaining healthy energy balance, cellular repair, and mitochondrial function – all factors linked to aging. However, direct evidence for a causal role of TSH in human longevity is weak. Studies show that both hyper- and hypothyroidism can be associated with increased mortality, but the optimal TSH range for longevity is not clearly defined. Many observations come from epidemiological studies that do not prove causation. Additionally, individual genetic factors (e.g., FOXO3 variants) may modulate TSH effects. The provided context contains no specific information on TSH and longevity. Therefore, caution is warranted: a TSH test alone is insufficient for longevity recommendations; clinical parameters and medical guidance are essential.