What should I know about genetische untersuchung?

Genetic testing, especially consumer DNA tests like MyBody-X, analyzes selected gene variants (e.g., APOA2, FADS, CLOCK, MC4R). They can offer clues about metabolism or chronotype but cannot diagnose conditions. Effect sizes are generally small (e.g., rs17782313 near MC4R: OR ~1.22–1.26 for BMI). The DIETFITS trial (JAMA 2018) showed genotype-based diets had no advantage over standard advice. Hormonal disorders like PCOS or thyroid issues are not assessed – clinical blood tests are required. Microbiome tests for perimenopause lack clinical validation (mechanistic evidence, no RCT). Results are population-specific and not deterministic. Beware of overinterpretation: a single SNP tells little. Evidence is mostly 'marketing' or 'mechanistic'. Always consult a doctor for health concerns.