The question of myths vs facts regarding celiac testing and fertility is important because untreated celiac disease can be linked to fertility issues. A celiac test (typically tTG-IgA) detects an autoimmune reaction to gluten, not directly a fertility disorder. Myth: Celiac only affects the gut – in reality, systemic inflammation and malabsorption of nutrients (e.g., iron, folate, zinc) can impair fertility. Fact: Screening for celiac is recommended in cases of unexplained infertility, as a gluten-free diet may improve fertility outcomes. However, the test alone is not a fertility test; a positive result requires medical follow-up. Caveat: Evidence comes from observational studies, not randomized controlled trials. The predictive value of a single biomarker is limited. Evidence: mixed.
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