What to watch with Zöliakie Test and fertility?

A celiac test (e.g., tTG-IgA, HLA-DQ2/DQ8) can be relevant for unexplained infertility, as untreated celiac disease may impair fertility through malabsorption and inflammation. However, the link is not universal, and testing should be guided by a physician to avoid misinterpretation. A gluten-free diet can improve fertility in confirmed celiac patients, but is not recommended without diagnosis. Evidence is based on observational studies, not large RCTs. Caveat: Genetic testing alone (HLA) does not confirm or exclude celiac disease—it only indicates predisposition. For those trying to conceive, a full diagnostic workup including duodenal biopsy remains the gold standard.