What to watch with Progesteron and menopause?

Progesterone is used in menopausal hormone therapy (MHT) primarily to protect the endometrium from estrogen-induced hyperplasia and cancer. Key watchpoints: Progesterone is only needed in women with a uterus. The choice between bioidentical progesterone and synthetic progestins should be individualized, as side effects (mood changes, breast tenderness, irregular bleeding) and risks (breast cancer, venous thromboembolism) differ. Evidence from large trials like the Women's Health Initiative (WHI) shows a nuanced risk-benefit profile. Timing matters: starting MHT within 10 years of menopause reduces cardiovascular risks. Regular gynecological follow-up and shared decision-making are essential. The provided context does not contain specific information on progesterone; this answer is based on general medical knowledge and clinical guidelines.