{"count":3,"index":{"built_at":"2026-07-28T06:48:05.484700+00:00","public_records":55311,"revision":"7fbeee94fe60cc8b67f1532a"},"query":{"area":null,"kind":null,"lang":null,"limit":10,"match_mode":"all_terms","q":"Evidence check: Vitamin D 25-OH in the context of fertility"},"results":[{"answer":"Vitamin D (25-OH) is increasingly discussed in the context of fertility. Observational studies suggest that low vitamin D levels are associated with reduced ovarian reserve, lower live birth rates after IVF, and poorer sperm quality in men. Mechanistically, vitamin D receptors are expressed in reproductive tissues and may influence hormone regulation and immune function. However, interventional trials show mixed results: some randomized controlled trials (RCTs) report improved pregnancy rates with supplementation, while others find no significant benefit. The evidence is therefore moderate – plausible biological pathways exist, but clinical utility remains uncertain. Correcting a deficiency is still advisable for overall health, but vitamin D testing alone is not a fertility solution. MyBody-X offers 25-OH measurement, but results should be integrated into a comprehensive fertility workup. Consumers should be cautious about overinterpreting single biomarkers.","area":"gesundheit","canonical_id":"gesundheit:canonical-bcd6e457c3bb50077fe7fca5","id":"public-2051c11ee6a23791f5da5782","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: Vitamin D 25-OH in the context of fertility","score":26.83813849,"snippet":"Vitamin D (25-OH) is increasingly discussed in the context of fertility. Observational studies suggest that low vitamin D levels are associated with reduced ovarian reserve, lower live birth rates after IVF, and poorer sperm quality in men. Mechanistically, vitamin D receptors are expressed in reproductive tissues and may influence hormone regulation and immune function. However, interventional trials show mixed results: some randomized controlled trials (RCTs) report improved pregnancy rates with supplementation, while others find no significant benefit. The evidence is therefore moderate – plausible biological pathways exist, but clinical utility remains uncertain. Correcting a deficiency ","sources":[],"title":"Evidence check: Vitamin D 25-OH in the context of fertility","url":"https://tikki.wiki/wissen/gesundheit/frage/public-2051c11ee6a23791f5da5782/evidence-check-vitamin-d-25-oh-in-the-context-of-fertility/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"The role of vitamin D (25-OH) in fertility is increasingly discussed, but the evidence is mostly moderate. Observational studies link low vitamin D levels to reduced fertility in women (e.g., longer cycle length, lower oocyte quality) and men (lower sperm quality). Randomized controlled trials (RCTs) are fewer and show mixed results: some report improved live birth rates after supplementation, others no significant effect. The German Nutrition Society (DGE) recommends a 25-OH-D level of at least 50 nmol/l, but no specific fertility guidelines exist. Important: deficiency should be confirmed by blood test before supplementing, as long-term high doses (e.g., >100 µg/day) can be toxic. Individual genetics (e.g., VDR variants) may influence vitamin D metabolism, but the effect is small. Overall, maintaining adequate vitamin D is sensible but not a magic bullet. Evidence is based on human studies of moderate quality, not strong RCTs.","area":"gesundheit","canonical_id":"gesundheit:canonical-3474f7a600465f532b323f64","id":"public-d97cbf5d96ba4f13b2f32eb5","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: Vitamin D 25-OH in the context of Fruchtbarkeit","score":26.32291461,"snippet":"The role of vitamin D (25-OH) in fertility is increasingly discussed, but the evidence is mostly moderate. Observational studies link low vitamin D levels to reduced fertility in women (e.g., longer cycle length, lower oocyte quality) and men (lower sperm quality). Randomized controlled trials (RCTs) are fewer and show mixed results: some report improved live birth rates after supplementation, others no significant effect. The German Nutrition Society (DGE) recommends a 25-OH-D level of at least 50 nmol/l, but no specific fertility guidelines exist. Important: deficiency should be confirmed by blood test before supplementing, as long-term high doses (e.g., >100 µg/day) can be toxic. Individu","sources":[],"title":"Evidence check: Vitamin D 25-OH in the context of Fruchtbarkeit","url":"https://tikki.wiki/wissen/gesundheit/frage/public-d97cbf5d96ba4f13b2f32eb5/evidence-check-vitamin-d-25-oh-in-the-context-of-fruchtbarkeit/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"The provided context does not directly address the Nährstoffcheck (nutrient check) from MyBody-X or its relation to fertility. It is well established that nutrient deficiencies—such as vitamin D, iron, folate, and zinc—can impact fertility. However, the tests mentioned in the context (Vitamin-D Selbsttest, Women's Wellness Check) are lifestyle tools, not medical diagnostics. The Vitamin-D test gives only an approximate 25-OH-D3 value, and the Women's Wellness Check does not specifically measure iron or vitamin D according to the context. There is no evidence from the context that the Nährstoffcheck measures fertility-related markers. Therefore, while a link between nutrient status and fertility is biologically plausible, the specific relationship with this product is unsupported by the given information. For fertility assessment, clinical lab testing and medical consultation are recommended. The evidence is rated as unclear because marketing claims cannot be distinguished from scientific evidence.","area":"gesundheit","canonical_id":"gesundheit:canonical-86a06770d32a16c63ef4a34d","id":"public-d9c20c7cb6077163ee6b7182","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"How are Nährstoffcheck and fertility related?","score":24.44501532,"snippet":"The provided context does not directly address the Nährstoffcheck (nutrient check) from MyBody-X or its relation to fertility. It is well established that nutrient deficiencies—such as vitamin D, iron, folate, and zinc—can impact fertility. However, the tests mentioned in the context (Vitamin-D Selbsttest, Women's Wellness Check) are lifestyle tools, not medical diagnostics. The Vitamin-D test gives only an approximate 25-OH-D3 value, and the Women's Wellness Check does not specifically measure iron or vitamin D according to the context. There is no evidence from the context that the Nährstoffcheck measures fertility-related markers. Therefore, while a link between nutrient status and fertil","sources":[],"title":"How are Nährstoffcheck and fertility related?","url":"https://tikki.wiki/wissen/gesundheit/frage/public-d9c20c7cb6077163ee6b7182/how-are-naehrstoffcheck-and-fertility-related/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}}],"schema_version":"tikki.search-response.v1"}