{"count":2,"index":{"built_at":"2026-07-27T16:47:47.246361+00:00","public_records":55311,"revision":"477639d366e691565fbe5d79"},"query":{"area":null,"kind":null,"lang":null,"limit":10,"match_mode":"all_terms","q":"Evidence check: Vitamin D 25-OH in the context of Sport"},"results":[{"answer":"Measuring 25-hydroxyvitamin D (25-OH vitamin D) in the context of sport is relevant because vitamin D is critical for bone health, muscle function, immune defense, and inflammation regulation. Deficiency can impair recovery, increase injury risk, and reduce performance. The evidence is nuanced: observational studies link low vitamin D levels with reduced muscle strength and higher infection rates. Randomized controlled trials (RCTs) show mixed results – in athletes with confirmed deficiency, supplementation improves outcomes like jump height or sprint time, while in replete individuals no additional performance benefit is seen. The MyBody-X test measures 25-OH vitamin D as a screening tool, but it has limitations: it is a single time-point measurement subject to seasonal variation and cannot determine causes or guide dosing. Self-interpretation without medical supervision is not recommended, as overdosing (hypercalcemia) carries risks. The evidence for the test itself is classified as 'practice' – it provides orientation, not diagnosis. For a sports medicine evaluation, additional factors such as training status, sun exposure, and individual genetics (e.g., VDR polymorphisms) should be considered. In summary, vitamin D testing is useful for at-risk groups (e.g., indoor athletes, winter season), but the evidence for performance enhancement in those with normal levels is weak.","area":"gesundheit","canonical_id":"gesundheit:canonical-304ddc44935bc2f074f940ab","id":"public-7050577a12c5028a516c94fb","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: Vitamin D 25-OH in the context of Sport","score":26.56588617,"snippet":"Measuring 25-hydroxyvitamin D (25-OH vitamin D) in the context of sport is relevant because vitamin D is critical for bone health, muscle function, immune defense, and inflammation regulation. Deficiency can impair recovery, increase injury risk, and reduce performance. The evidence is nuanced: observational studies link low vitamin D levels with reduced muscle strength and higher infection rates. Randomized controlled trials (RCTs) show mixed results – in athletes with confirmed deficiency, supplementation improves outcomes like jump height or sprint time, while in replete individuals no additional performance benefit is seen. The MyBody-X test measures 25-OH vitamin D as a screening tool, ","sources":[],"title":"Evidence check: Vitamin D 25-OH in the context of Sport","url":"https://tikki.wiki/wissen/gesundheit/frage/public-7050577a12c5028a516c94fb/evidence-check-vitamin-d-25-oh-in-the-context-of-sport/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"The vitamin D receptor (VDR) is often discussed in sports contexts because it influences muscle strength, bone metabolism, and immune function. Polymorphisms such as FokI (rs2228570) and BsmI (rs1544410) have been associated with differences in muscle mass, strength gains after training, and injury risk. However, the evidence is mixed: many studies are small, fail to replicate, or show only weak effects. Moreover, the impact is strongly modulated by actual vitamin D status – a genetic disadvantage can often be compensated by adequate levels. Therefore, a VDR gene test alone does not allow specific training or nutrition recommendations. It is more useful to measure serum 25(OH)-vitamin D levels. Supplementation should only be done if deficiency is confirmed, as overdosing is harmful. In the context of MyBody-X, note that their DNA tests for athletes often include markers with small effect sizes; clinical relevance is limited. In summary, VDR variants have a detectable but small influence on athletic performance parameters. The evidence does not support personalized training plans based solely on this gene.","area":"gesundheit","canonical_id":"gesundheit:canonical-4552ffb41768ae31e84b9c67","id":"public-5fb617dfae5d95add08d9a75","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: VDR in the context of Sport","score":24.38857364,"snippet":"The vitamin D receptor (VDR) is often discussed in sports contexts because it influences muscle strength, bone metabolism, and immune function. Polymorphisms such as FokI (rs2228570) and BsmI (rs1544410) have been associated with differences in muscle mass, strength gains after training, and injury risk. However, the evidence is mixed: many studies are small, fail to replicate, or show only weak effects. Moreover, the impact is strongly modulated by actual vitamin D status – a genetic disadvantage can often be compensated by adequate levels. Therefore, a VDR gene test alone does not allow specific training or nutrition recommendations. It is more useful to measure serum 25(OH)-vitamin D leve","sources":[],"title":"Evidence check: VDR in the context of Sport","url":"https://tikki.wiki/wissen/gesundheit/frage/public-5fb617dfae5d95add08d9a75/evidence-check-vdr-in-the-context-of-sport/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}}],"schema_version":"tikki.search-response.v1"}