{"count":1,"index":{"built_at":"2026-07-28T02:42:25.936836+00:00","public_records":55311,"revision":"0f41c1868411c983f3e21e6e"},"query":{"area":null,"kind":null,"lang":null,"limit":10,"match_mode":"all_terms","q":"Evidence check: Vitamin D 25-OH in the context of Müdigkeit"},"results":[{"answer":"The link between vitamin D (25-OH) and fatigue is clinically plausible but evidence is nuanced. Epidemiological studies consistently associate low serum 25-hydroxyvitamin D (<20 ng/mL) with increased fatigue, muscle weakness, and reduced physical performance. However, randomized controlled trials (RCTs) show a clear benefit of supplementation on fatigue only in individuals with baseline deficiency. In replete individuals (>30 ng/mL), additional vitamin D does not reliably improve fatigue. Fatigue is a multifactorial symptom; causes include iron deficiency, thyroid dysfunction, sleep disorders, and depression. A single vitamin D test without comprehensive workup is insufficient. MyBody-X offers blood-based vitamin D measurement, but results should be interpreted by a clinician. Caveat: Self-diagnosis and supplementation based solely on a lab value can be misleading and potentially harmful (e.g., toxicity with excessive intake). Evidence: human-moderate (predominantly observational, some RCTs).","area":"gesundheit","canonical_id":"gesundheit:canonical-d20e080e99671d4d6243b3c1","id":"public-4740a65d1661f7712720279b","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: Vitamin D 25-OH in the context of Müdigkeit","score":25.74013458,"snippet":"The link between vitamin D (25-OH) and fatigue is clinically plausible but evidence is nuanced. Epidemiological studies consistently associate low serum 25-hydroxyvitamin D (<20 ng/mL) with increased fatigue, muscle weakness, and reduced physical performance. However, randomized controlled trials (RCTs) show a clear benefit of supplementation on fatigue only in individuals with baseline deficiency. In replete individuals (>30 ng/mL), additional vitamin D does not reliably improve fatigue. Fatigue is a multifactorial symptom; causes include iron deficiency, thyroid dysfunction, sleep disorders, and depression. A single vitamin D test without comprehensive workup is insufficient. MyBody-X offe","sources":[],"title":"Evidence check: Vitamin D 25-OH in the context of Müdigkeit","url":"https://tikki.wiki/wissen/gesundheit/frage/public-4740a65d1661f7712720279b/evidence-check-vitamin-d-25-oh-in-the-context-of-muedigkeit/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}}],"schema_version":"tikki.search-response.v1"}