{"count":2,"index":{"built_at":"2026-07-27T11:23:18.466704+00:00","public_records":55311,"revision":"cee071df6e2aeed47426c28b"},"query":{"area":null,"kind":null,"lang":null,"limit":10,"match_mode":"all_terms","q":"Evidence check: Vitamin D 25-OH in the context of Haut"},"results":[{"answer":"The provided context does not contain specific data on Vitamin D 25-OH in relation to skin. Generally, vitamin D is known to play a role in skin health, including regulation of inflammation and cell proliferation. Deficiency has been associated with skin conditions like psoriasis and acne, but evidence for routine testing in healthy individuals without risk factors is limited. Measurement of 25-OH vitamin D is well-established, but its utility for skin issues alone is not supported by large randomized trials. MyBody-X offers a vitamin D test, but interpretation should consider overall health context. A single value does not directly reflect skin health, as many factors (UV exposure, diet, genetics) are involved. Evidence is rated as moderate, based on observational and mechanistic studies. Caveat: No direct sources from the provided context.","area":"gesundheit","canonical_id":"gesundheit:canonical-0129610150b6328861c4a02c","id":"public-03d39a2527c7f57dcf39990a","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: Vitamin D 25-OH in the context of Haut","score":25.67451895,"snippet":"The provided context does not contain specific data on Vitamin D 25-OH in relation to skin. Generally, vitamin D is known to play a role in skin health, including regulation of inflammation and cell proliferation. Deficiency has been associated with skin conditions like psoriasis and acne, but evidence for routine testing in healthy individuals without risk factors is limited. Measurement of 25-OH vitamin D is well-established, but its utility for skin issues alone is not supported by large randomized trials. MyBody-X offers a vitamin D test, but interpretation should consider overall health context. A single value does not directly reflect skin health, as many factors (UV exposure, diet, ge","sources":[],"title":"Evidence check: Vitamin D 25-OH in the context of Haut","url":"https://tikki.wiki/wissen/gesundheit/frage/public-03d39a2527c7f57dcf39990a/evidence-check-vitamin-d-25-oh-in-the-context-of-haut/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}},{"answer":"The vitamin D receptor (VDR) is frequently discussed in the context of skin health, particularly psoriasis, skin barrier function, and premature aging. The evidence is moderate: human observational studies and GWAS have linked VDR polymorphisms (e.g., FokI, TaqI) to psoriasis risk, but effect sizes are small and replication inconsistent. For direct anti-aging effects (collagen, elasticity), robust clinical trials are lacking; most data come from cell or animal models. VDR does influence keratinocyte differentiation and local vitamin D activation, which is biologically plausible, but a personalized recommendation based solely on a genetic test is not evidence-based. Caveat: Vitamin D supplementation should not be guided by a VDR test alone – blood levels of 25(OH)D are clinically more relevant. MyBody-X tests provide orienting hints, not diagnoses.","area":"gesundheit","canonical_id":"gesundheit:canonical-d586e65cefa4cf71316f9173","id":"public-e6fe4e3eb6cddc662babb181","kind":"qa","language":"en","publication_status":"existing_native_answer_privacy_screened_sources_pending","question":"Evidence check: VDR in the context of Haut","score":23.13633673,"snippet":"The vitamin D receptor (VDR) is frequently discussed in the context of skin health, particularly psoriasis, skin barrier function, and premature aging. The evidence is moderate: human observational studies and GWAS have linked VDR polymorphisms (e.g., FokI, TaqI) to psoriasis risk, but effect sizes are small and replication inconsistent. For direct anti-aging effects (collagen, elasticity), robust clinical trials are lacking; most data come from cell or animal models. VDR does influence keratinocyte differentiation and local vitamin D activation, which is biologically plausible, but a personalized recommendation based solely on a genetic test is not evidence-based. Caveat: Vitamin D suppleme","sources":[],"title":"Evidence check: VDR in the context of Haut","url":"https://tikki.wiki/wissen/gesundheit/frage/public-e6fe4e3eb6cddc662babb181/evidence-check-vdr-in-the-context-of-haut/","verification":{"claim_support_verified":false,"human_reviewed":false,"quote_exact_match":false,"source_identity_verified":false,"tier":"existing_native_answer_privacy_screened_sources_pending"}}],"schema_version":"tikki.search-response.v1"}